Which of the following is an example of a DMARD?

Disease-Modifying Anti-Rheumatic Drugs (DMARDs) are a category of medication specifically designed to slow down the progression of rheumatoid arthritis and other autoimmune diseases. They help improve quality of life by altering the disease process rather than just alleviating symptoms.

Orencia (Abatacept) fits this definition as it is a biologic DMARD that works by inhibiting the activation of T-cells, which play a significant role in the inflammatory process associated with these chronic conditions. This mechanism allows the drug to reduce inflammation and prevent joint damage over time.

In contrast, the other options listed do not qualify as DMARDs. Ibuprofen and aspirin are nonsteroidal anti-inflammatory drugs (NSAIDs), which relieve pain and reduce inflammation but do not modify the disease itself. Prednisone is a corticosteroid that can also manage symptoms and inflammation but does not have the disease-modifying properties of a DMARD. Therefore, Orencia (Abatacept) is identified as the correct example of a DMARD due to its specific role in altering the course of the disease rather than simply treating the symptoms.