Which drug is known to enhance the transmission of norepinephrine and dopamine, leading to appetite suppression?

Diethylpropion, known by its brand name Tenuate, functions primarily as an appetite suppressant. It does this through its mechanism of action, which involves the enhancement of norepinephrine and dopamine transmission in the brain. By increasing the levels of these neurotransmitters, diethylpropion can help reduce hunger signals, contributing to weight loss efforts in individuals struggling with obesity. This is why it is effective as a short-term adjunct in a weight management program.

The other options, while they may address issues related to weight loss or appetite in different ways, do not primarily operate through the enhancement of norepinephrine and dopamine. Phentermine also acts as a stimulant affecting similar pathways, but diethylpropion is specifically noted for its unique profile in neurotransmitter modulation. Bupropion has antidepressant properties and can help in weight management, but its primary use is not as an appetite suppressant like diethylpropion. Orlistat is focused on inhibiting fat absorption rather than altering neurotransmitter levels or appetite directly.