Which auxiliary label would be appropriate for a medication that must be taken with food?

The label indicating "Take with food" is appropriate for medications that require food to enhance absorption or reduce gastrointestinal irritation. This instruction helps ensure that the medication is more effective and minimizes potential side effects that could arise from taking it on an empty stomach. For instance, certain medications may be better tolerated when the stomach is not empty, thereby preventing nausea or discomfort.

In the context of the other labels: "Shake Well" is relevant for suspensions or solutions that require mixing before administration, while "May cause drowsiness" provides a warning for medications that can impair alertness, and "Take on an empty stomach" is contradictory to the requirement for this medication. Therefore, "Take with food" directly addresses the specific instructions necessary for optimal use of the medication in question.