What is a common side effect of using Glucophage?

Gastrointestinal upset is a well-documented common side effect of Glucophage, which is the brand name for metformin, a medication primarily used to manage type 2 diabetes. Patients often report symptoms such as nausea, vomiting, diarrhea, and abdominal discomfort during the initial phase of treatment or when the dosage is increased. These side effects typically occur due to the way metformin interacts with the gastrointestinal system, particularly its impact on the gut microbiota and its effect on glucose metabolism.

In contrast, other side effects associated with medications may not apply to Glucophage in the same way. For example, weight gain is generally not associated with metformin; in fact, it is often noted for its potential to assist in weight loss or weight neutrality. Increased heart rate and dry mouth are not common side effects linked to metformin and are more often associated with other classes of medications or different underlying health conditions. Thus, gastrointestinal upset stands out as the most relevant and expected side effect of Glucophage.