How much water should be added when initially reconstituting an oral suspension?

When reconstituting an oral suspension, the amount of water to add is typically specified in the manufacturer's instructions, which are based on achieving the correct concentration and consistency of the medication. The choice of adding 2/3 of the total required volume is often the standard recommendation because it allows for the powder to dissolve properly while ensuring the suspension maintains the necessary viscosity and effectiveness.

Adding the right amount of water is crucial for ensuring the medication's stability and therapeutic efficacy. Too little water may result in a thick, clumpy suspension that is difficult to dose accurately, while too much water can lead to a dilute solution that may not deliver the intended dose of the active ingredient.

Using 2/3 of the water ensures that there is enough liquid for proper dissolution, enabling the active ingredients to be evenly distributed in the suspension, which is essential for consistent dosing. The other choices may not provide the appropriate amount of water needed for effective reconstitution based on standard practices in pharmacy.